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Reasons for Antiretroviral Treatment Change Among Adult HIVAIDS Patients at Nedjo General Hospital, Western Ethiopia
| Content Provider | Semantic Scholar |
|---|---|
| Author | Fekadu, Ginenus Bati, Lencho Gebeyehu, Habte |
| Copyright Year | 2019 |
| Abstract | From a total of 117 included patients, 50.4% were females and the median (IQR) age of the patients was 28 (24-47) years. Majority of patients, 63 (53.9%) started their treatment at world health organization (WHO) clinical stage III (53.9%) and CD4 count of between 200-350 cells/mm3 (44.54%). At the beginning of ART, 56 (47.9%) patients were on a fixed-dose combination of stavudine-lamivudine-nevirapine (D4T/3TC/NVP). The single-drug substitutions were D4T (n = 63), NVP (n = 34), AZT (n =5), EFV (n = 2), and TDF (n = 1). Majority of the patients, 35(29.9%) switched their initial ART regimen after 3 years of regimen commencement. The common reasons reported for initial regimen change was availability of new drug 46 (39.3%) followed by toxicity/side effects 34 (29.2%). From all toxicities, peripheral neuropathy (47.1%) was the most common toxicity followed by rash (20.6%). After regimen change, 47 (40.2%) were received AZT+3TC+NVP. |
| Starting Page | 65 |
| Ending Page | 73 |
| Page Count | 9 |
| File Format | PDF HTM / HTML |
| DOI | 10.2174/1874613601913010065 |
| Volume Number | 13 |
| Alternate Webpage(s) | https://benthamopen.com/contents/pdf/TOAIDJ/TOAIDJ-13-65.pdf |
| Alternate Webpage(s) | https://doi.org/10.2174/1874613601913010065 |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
