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Evidence that neurokinin A (substance K) neurons project from the striatum to the substantia nigra in rats
| Content Provider | Semantic Scholar |
|---|---|
| Author | Nagashima, Akira Takano, Yukio Masui, H. Kamiya, Hiro-O |
| Copyright Year | 1987 |
| Abstract | The striatonigral neurokinin A (NKA) pathway in rats was examined with an antiserum specific to the N-terminal region of NKA. Thermal lesions of the striatum decreased both substance P-like immunoreactivity (SP-LI) and NKA-like immunoreactivity (NKA-LI) in the substantia nigra (SN). The releases of SP-LI and NKA-LI in the SN were measured by a push pull superfusion technique. Addition of 50 mM K+ to the superfusion medium increased the releases of both SP-LI and NKA-LI to 1.5-2.0 times the basal values. These results suggest that NKA neurons as well as SP neurons in the striatum project to the SN in rats. |
| Starting Page | 103 |
| Ending Page | 108 |
| Page Count | 6 |
| File Format | PDF HTM / HTML |
| DOI | 10.1016/0304-3940(87)90615-X |
| PubMed reference number | 3037449 |
| Journal | Medline |
| Volume Number | 77 |
| Alternate Webpage(s) | https://api.elsevier.com/content/article/pii/030439408790615X |
| Alternate Webpage(s) | https://www.sciencedirect.com/science/article/pii/030439408790615X?dgcid=api_sd_search-api-endpoint |
| Alternate Webpage(s) | https://doi.org/10.1016/0304-3940%2887%2990615-X |
| Journal | Neuroscience Letters |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
