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Activation CBF Varied by Perturbation of PaCO2 and PaO2 Level: PET Study
| Content Provider | Semantic Scholar |
|---|---|
| Author | Kanno, Iwao Shimosegawa, Eku Fujita, Hideaki Hatazawa, Jun |
| Copyright Year | 2001 |
| Abstract | The quantitative aspect of cerebral blood flow (CBF) caused by neuronal activation has been approached using positron-emission tomography in humans. We measured the magnitude of CBF activation for neuronal stimulation under perturbations of PaCO2 and PaO2. In the PaCO2 perturbation study we found that CBF change was nearly proportional to the baseline CBF, which implied that the magnitude of the activation CBF was independent of that of the delivery of O2 or nutritious substrates. In the PaO2 perturbation study, we found that hyperoxia (PaO2 ~470 mmHg) elevated the magnitude of the activation CBF, which suggests that the interaction of oxygen accelerates the mediator activity on neurovascular coupling. |
| Starting Page | 221 |
| Ending Page | 225 |
| Page Count | 5 |
| File Format | PDF HTM / HTML |
| DOI | 10.1007/978-4-431-67899-1_27 |
| Volume Number | 48 |
| Alternate Webpage(s) | https://www.jstage.jst.go.jp/article/kjm1952/48/supplement2/48_supplement2_A49/_pdf |
| Alternate Webpage(s) | https://doi.org/10.1007/978-4-431-67899-1_27 |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
