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New technique for estimating thresholds of toxicity in ecological risk assessment.
| Content Provider | Semantic Scholar |
|---|---|
| Copyright Year | 2002 |
| Abstract | The use and utility of the no observed effect concentration (NOEC) in ecological risk assessment is a contentious issue. One concern is that the NOEC is not representative of a concentration at which no biologically significant effect is occurring. A new method has been developed to estimate the threshold of toxicity, or a true NOEC, for aquatic plants. The method involves determining the effective concentration (ECx) of a number of endpoints from one species. These ECx values are plotted on a log-probability scale. The x-intercept, or a low centile, of the distribution can be interpreted as the threshold of toxicity for that plant at that response level. This threshold is the concentration at which no effects should be observed for any endpoint above that response level. It is based on the assumptions that multiple effect measures from a single species will be log-normally distributed and thatthe distribution contains all possible endpoints for that species. The thresholds and the distributions can then be used as a substitute for the NOEC or ECx in risk assessment techniques, such as hazard quotients and probabilistic ecological risk assessment. This new method of estimating toxicitythresholds is more realistic than the use of arbitrary uncertainty factors, is more conservative than current probabilistic risk assessment methods, allows for simple comparison between species and exposure duration to a toxicant, and may be useful for assessing mixture toxicity. This technique was applied to field derived data with Lemna gibba, Myriophyllum spicatum, and M. sibiricumto assess potential risks from monochloroacetic acid (MCA). Using this new risk assessment method, we conclude that MCA does not appear to pose a risk to aquatic macrophytes under field conditions at current environmental concentrations. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | https://www.math.tecnico.ulisboa.pt/~apires/pe/ExEst_1_Ambiente.pdf |
| PubMed reference number | 12188350v1 |
| Volume Number | 36 |
| Issue Number | 15 |
| Journal | Environmental science & technology |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | 20-Methylcholanthrene Adverse reaction to drug Clerodendranthus spicatus Estimated Intercept Substance Lemna minuta chloroacetic acid |
| Content Type | Text |
| Resource Type | Article |
