NDLI: The effect of repetitive transcranial magnetic stimulation (rTMS) on symptoms in obsessive compulsive disorder. A randomized, double blind, sham controlled study.

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The effect of repetitive transcranial magnetic stimulation (rTMS) on symptoms in obsessive compulsive disorder. A randomized, double blind, sham controlled study.

Content Provider	Semantic Scholar
Author	Praško, Ján Pasková, Beáta Záleský, Richard Novák, Tomáš Dvořáčková Blanka Kopecek, Miloslav Bares, Martin Horácek, Jirí
Copyright Year	2006
Abstract	BACKGROUND The goal of our study is to assess whether transcranial magnetic stimulation (rTMS) would facilitate the effect of antidepressant in OCD patients. METHOD The aim of the randomized, double-blind, sham controlled study was to compare the 2 and 4 week efficacy of the 10 sessions rTMS with sham rTMS in serotonin reuptake inhibitor resistant OCD patient. Thirty three right-handed patients were randomly assigned to either active rTMS or to sham rTMS. Active rTMS with the frequency of 1 Hz at 110% of motor threshold (MT) was administered over the left dorso-lateral prefrontal cortex. The same time schedule was used for sham administration. Thirty patients finished the study, three patients' dropped out at the beginning. Psychopathology was assessed by CGI, HAMA, Y-BOCS and BAI before the treatment, immediately after the experimental treatment, and 2 weeks after the experimental treatment by an independent reviewer. RESULTS Both groups improved during the study period but the treatment effect did not differ between them in any of the instruments. CONCLUSION Low frequency rTMS administered over the left dorso-lateral prefrontal cortex during 10 daily sessions did not differ from sham rTMS in facilitating the effect of serotonin reuptake inhibitors in OCD patients.
File Format	PDF HTM / HTML
Alternate Webpage(s)	http://www.nel.edu/userfiles/articlesnew/NEL270306A15.pdf
PubMed reference number	16816829
Volume Number	27
Issue Number	3
Journal	Neuro endocrinology letters
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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