NDLI: Relevance of the Application of Pharmacokinetic-Pharmacodynamic Modelling Concepts in Drug Development

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Relevance of the Application of Pharmacokinetic-Pharmacodynamic Modelling Concepts in Drug Development

Content Provider	Semantic Scholar
Author	Breimer, D. D. Danhof, Meindert
Copyright Year	1997
Abstract	In the past decade considerable progress has been made in the field of integrated pharmacokineticpharmacodynamic modelling, as can be deduced from the considerable increase in the number of papers on pharmacokinetics-pharmacodynamics in recent clinical pharmacological and pharmaceutical journals, both on the more theoretical modelling issues and on application. Furthermore, compilations of information on pharmacokinetic-pharmacodynamic modelling in the form of textbooks have become available.[1-31 Further contributions to the discussion of pharmacokineticpharmacodynamic modelling were made at the first and second international symposia on Measurement and Kinetics of In Vivo Drug Effects in Leiden in 1990 and 1994, at the symposium on Integration ofPharmacokinetics, Pharmacodynamics and Toxicokinetics in Rational Drug Development in Washington in 1991 and at the symposium on New Strategies in Drug Development and Clinical Evaluation: The Population Approach in Manchester, also in 1991.[4]
Starting Page	259
Ending Page	267
Page Count	9
File Format	PDF HTM / HTML
DOI	10.2165/00003088-199732040-00001
PubMed reference number	9113436
Journal	Medline
Volume Number	32
Alternate Webpage(s)	https://page-one.springer.com/pdf/preview/10.2165/00003088-199732040-00001
Journal	Clinical pharmacokinetics
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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