NDLI: Dementia pugilistica with clinical features of Alzheimer's disease.

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Dementia pugilistica with clinical features of Alzheimer's disease.

Content Provider	Semantic Scholar
Author	Areza-Fegyveres, Renata Rosemberg, Sérgio Castro, Rosa Maria R. P. S. Porto, Cláudia Sellitto Bahia, Valéria Santoro Caramelli, Paulo Nitrini, Ricardo
Copyright Year	2007
Abstract	A 61-year-old ex-boxer presented with a three-year history of progressive memory decline. During a seven-year follow-up period, there was a continuous cognitive decline, very similar to that usually observed in Alzheimer's disease. Parkinsonian, pyramidal or cerebellar signs were conspicuously absent. Neuropathological examination revealed the typical features of dementia pugilistica: cavum septi pellucidi with multiple fenestrations, numerous neurofibrillary tangles in the cerebral isocortex and hippocampus (and rare senile plaques). Immunohistochemistry disclosed a high number of tau protein deposits and scarce beta-amyloid staining. This case shows that dementia pugilistica may present with clinical features practically undistinguishable from Alzheimer's disease.
Starting Page	95
Ending Page	102
Page Count	8
File Format	PDF HTM / HTML
Alternate Webpage(s)	http://www.scielo.br/pdf/anp/v65n3b/19.pdf
Alternate Webpage(s)	http://www.scielosp.org/pdf/anp/v65n3b/19.pdf
PubMed reference number	17952290v1
Volume Number	65
Issue Number	3B
Journal	Arquivos de neuro-psiquiatria
Language	English
Access Restriction	Open
Subject Keyword	Alzheimer's Disease Cognition Disorders Diffuse Neurofibrillary Tangles with Calcification Frontotemporal dementia Memory Disorders Multi-infarct dementia Neocortex Parkinson Disease Senile Plaques boxer dog
Content Type	Text
Resource Type	Article

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