Loading...
Please wait, while we are loading the content...
Similar Documents
Determination of Sulfate and Sulfamate in Topiramate Using a Reagent-Free Ion Chromatography System
| Content Provider | Semantic Scholar |
|---|---|
| Author | Kornfeld, Richard P. Borba, Brian M. De |
| Copyright Year | 2016 |
| Abstract | Introduction Epilepsy is a common neurological disorder that can cause anywhere from a brief cessation of responsiveness to severe muscle spasms with a loss of consciousness.1 This condition is usually controlled with antiepileptic drugs (AEDs). However, approximately 20% of patients with epilepsy are resistant to therapy with first-generation AEDs.2 Topiramate (Topamax®) is a second-generation AED approved by the FDA for the treatment of partial seizures (with or without secondarily generalized seizures), seizures associated with Lennox Gastaut Syndrome, and primary generalized tonic-clonic seizures in patients that are inadequately controlled by conventional first-generation AEDs.3 Topiramate has also been shown to be effective in the prophylactic treatment of migraine headaches. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://tools.thermofisher.com/content/sfs/brochures/80929-AN238-IC-Topiramate-Sulfate-03Sept2009-LPN2316.pdf |
| Alternate Webpage(s) | http://tools.thermofisher.com/content/sfs/brochures/AN-238-IC-Sulfate-Sulfamate-Topiramate-RFIC-AN71942-EN.pdf |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
