NDLI: Antioxidant Activity of Spilanthes Acmella Extracts

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Antioxidant Activity of Spilanthes Acmella Extracts

Content Provider	Semantic Scholar
Author	Rao, Talluri Mallikarjuna Rao, Battu Ganga Rao, Yadavalli Venkateswara
Copyright Year	2012
Abstract	Many medicinal plants were with a long history of use in folk medicine against a variety of diseases. Recently, many researchers have taken a great interest on medicinal plants for their phytochemical constituents and biological activities including antioxidant activity. The present study was aimed to evaluate phytochemical analysis, quantification of total phenolic, alkaloid contents and antioxidant activity of Spilanthes acmella extracts (70% Ethanol, Methanol, Ethyl Acetate and Hexane). The total phenolic and alkaloid contents were quantified by using gallic acid and atropine are as standards and antioxidant activity was evaluated by using three free radicals (Superoxide, Hydroxyl and DPPH). Spilanthes acmella extracts revealed the presence of different phytochemical constituents like steroids, terpenoids, flavanoids, alkaloids, glycosides, tannins, carbohydrates, oils and amino acids. The methanol extract have more phenolic and alkaloid contents i.e. 38.83±0.68 (mg/gm) and 26.37±0.16 (mg/gm) than other extracts. The extracts were produced concentration dependent percentage inhibition on free radicals and produced maximum activity at concentrations of 320 and 640μg. Among all extracts, methanolic extract showed better activity compared to other extracts with mean IC50 values on superoxide, hydroxyl and DPPH radicals were 189μg, 153μg and 313μg. The above results suggest that Spilanthes acmella extracts have antioxidant activity. Further research is in progress i.e. to isolation and characterization of active molecules (compounds) responsible for the antioxidant activity which can be used to treat various diseases.
File Format	PDF HTM / HTML
Alternate Webpage(s)	http://www.onlineijp.com/download.php?f=152_216-220.pdf&id=152
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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