Loading...
Please wait, while we are loading the content...
Similar Documents
IMG-ABC: An Atlas of Biosynthetic Gene Clusters to Fuel the Discovery of Novel Secondary Metabolites
| Content Provider | Semantic Scholar |
|---|---|
| Author | Chen, I-Min A. Ratner, Anna Palaniappan, Krishna Huang, Jinghua Reddy, T. B. K. Cimermancic, Peter Fischbach, Michael A. Ivanova, Natalia N. Markowitz, Victor M. Kyrpides, Nikos C. Pati, Amrita |
| Copyright Year | 2014 |
| Abstract | In the discovery of secondary metabolites (SMs), large-scale analysis of sequence data is a promising exploration path that remains largely underutilized due to the lack of relevant computational resources. We present IMG-ABC (https://img.jgi.doe.gov/abc/) -- An Atlas of Biosynthetic gene Clusters within the Integrated Microbial Genomes (IMG) system1. IMG-ABC is a rich repository of both validated and predicted biosynthetic clusters (BCs) in cultured isolates, single-cells and metagenomes linked with the SM chemicals they produce and enhanced with focused analysis tools within IMG. The underlying scalable framework enables traversal of phylogenetic dark matter and chemical structure space -- serving as a doorway to a new era in the discovery of novel molecules. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | https://cloudfront.escholarship.org/dist/prd/content/qt9b64p7jh/qt9b64p7jh.pdf?t=p0i3os |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
