NDLI: Blood Collection Tubes and the Impact on Clinical Analysis of Total T3 and Total T4 in Radioimmunoassay

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Blood Collection Tubes and the Impact on Clinical Analysis of Total T3 and Total T4 in Radioimmunoassay

Content Provider	Semantic Scholar
Author	Chang, Jin-Biou Huang, Chih-Heng Chiu, Jainn-Shiun Chuang, Mei-Hua Tien, Hui-Lan Wang, Yuh-Feng
Copyright Year	2007
Abstract	Background: Accurate laboratory studies are essential for accurate diagnosis. However, several factors may affect test results. This study sought to identify the impacts of two different collecting tubes on clinical analysis results. Methods: Glass and plastic collection tubes were used for blood collection in 970 subjects. Two thyroid related hormones, total triiodothyronine (TT3) and total thyroxine (TT4), were examined by means of radioimmunoassay. Blood samples were collected into the tubes simultaneously and randomly. Results: Test values were significantly higher among specimens in glass BD Vacutainer(superscript TM) tube than the plastic BD Vacutainer SST(superscript TM) tube (TT3: 113.7ng/dL vs. 110.3ng/dL; P＜0.0001 and TT4: 8.5µg/dL vs. 8.39µg/dL; P=0.0013). Regression analysis by Passing-Boblok method revealed there is no definite difference in the TT3. However, negative proportional difference was found in TT4 analysis. Conclusion: The collection tube can influence analytic outcomes. Medical laboratories should pay more attention to variations in results caused by different collecting tubes.
Starting Page	201
Ending Page	208
Page Count	8
File Format	PDF HTM / HTML
DOI	10.6332/ANMS.2004.004
Volume Number	20
Alternate Webpage(s)	http://www.snm.org.tw/revista2006/2006-08/journal9409/pdf/v20n4/AnnNuclMedSCi07-20-201(Chang-4).pdf
Alternate Webpage(s)	https://doi.org/10.6332/ANMS.2004.004
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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