Inoperable chronic thromboembolic pulmonary hypertension treated with riociguat: A case studyInoperable chronic thromboembolic pulmonary hypertension

Content Provider	Semantic Scholar
Author	Ortiz-Bautista, Carlos Ochoa-Parra, Nuria Navas-Tejedor, Paula Moran-Fernandez, Laura Gómez-Sánchez, Miguel Angel
Copyright Year	2015
Abstract	Abstract A 51-year-old woman presented with a one-year history of progressive dyspnea, WHO functional class III-IV and exercise-related syncope. Transthoracic echocardiography and computed tomography pulmonary angiography were performed, leading to a diagnosis of pulmonary arterial hypertension. She was referred to our pulmonary hypertension unit, where a complete study was performed, including ventilation/perfusion scan, which was consistent with chronic thromboembolic pulmonary hypertension. Risk factors for this condition were excluded and therapeutic options were evaluated. Imaging studies showed distal pulmonary disease so pulmonary endarterectomy was rejected. Further therapeutic options were evaluated and the patient was subsequently enrolled in an open-label uncontrolled trial with riociguat. After one year of treatment, significant improvement in functional class, 6-minute walk test and NT-proBNP were seen, without significant secondary effects.
Starting Page	777
Ending Page	777
Page Count	1
File Format	PDF HTM / HTML
DOI	10.1016/j.repce.2015.12.007
Volume Number	34
Alternate Webpage(s)	https://www.revportcardiol.org/index.php?p=revista&pii=S2174204915002846&tipo=pdf-simple
Alternate Webpage(s)	https://doi.org/10.1016/j.repce.2015.12.007
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article