NDLI: Organocatalyzed asymmetric vinylogous Michael addition of α,β-unsaturated γ-butyrolactam.

Content Provider	Semantic Scholar
Author	Zhang, Jinlong Liu, Xihong Ma, Xiaojuan Wang, Rui
Copyright Year	2013
Abstract	Highly efficient asymmetric vinylogous 1,6-Michael addition of α,β-unsaturated γ-butyrolactam to 3-methyl-4-nitro-5-alkenyl-isoxazoles and Michael addition to trichloromethyl ketones by using a chiral quinine-derived squaramide organocatalyst were described, giving products with high diastereo- and enantioselectivities (up to >25 : 1 dr and 96% ee).
File Format	PDF HTM / HTML
DOI	10.1039/c3cc44059a
PubMed reference number	24000339
Journal	Medline
Volume Number	49
Issue Number	81
Alternate Webpage(s)	http://www.rsc.org/suppdata/cc/c3/c3cc44059a/c3cc44059a.pdf
Journal	Chemical communications
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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