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Blood pressure and mortality among ESRD patients: all patients are not created equal.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Crews, Deidra C. Powe, Neil R. |
| Copyright Year | 2010 |
| Abstract | The annual risk for mortality is extremely high for patients who have ESRD and are treated with dialysis in the United States,1 and cardiovascular disease persists as their most common cause of death.2 Hypertension affects the majority of hemodialysis patients, and most have what would be considered uncontrolled hypertension.3 However, appropriate BP targets for these patients remain uncertain and have largely been extrapolated from studies conducted of the general population. The Kidney Disease Outcomes Quality Initiative (KDOQI) Work Group on this subject offered an opinion of “a reasonable goal is predialysis BP <140/90 mmHg,” but the evidence to support their statement was reported as weak.4 The weakness of this conclusion stems partly from the exclusion of patients with ESRD from randomized trials involving antihypertensive drugs and BP targets, thereby leaving nephrologists to rely on observational data for guidance on the best approach to manage BP in dialysis patients. Adding to the problem, these epidemiologic data are not always in agreement in their reported relationship between BP and mortality, and their findings vary on a number of factors, including when BP was analyzed (before versus after dialysis), whether early (1 to 2 years) versus late (>3 years) mortality was assessed, and whether pulse pressure … |
| File Format | PDF HTM / HTML |
| DOI | 10.1681/ASN.2010090971 |
| PubMed reference number | 20947629 |
| Journal | Medline |
| Volume Number | 21 |
| Issue Number | 11 |
| Alternate Webpage(s) | https://www.researchgate.net/profile/Deidra_Crews/publication/47429208_Blood_Pressure_and_Mortality_among_ESRD_Patients_All_Patients_Are_Not_Created_Equal/links/549743220cf20f487d31661e.pdf?origin=publication_detail |
| Alternate Webpage(s) | https://doi.org/10.1681/ASN.2010090971 |
| Journal | Journal of the American Society of Nephrology : JASN |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
