NDLI: Chronic ethanol-induced glial fibrillary acidic protein (GFAP) immunoreactivity: an immunocytochemical observation in various regions of adult rat brain.

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Chronic ethanol-induced glial fibrillary acidic protein (GFAP) immunoreactivity: an immunocytochemical observation in various regions of adult rat brain.

Content Provider	Semantic Scholar
Author	Dalçik, Hakki Yardimoglu, Melda Y. Filiz, Serdar Gonca, Süheyla Dalçik, Cannur Erden, Bekir Faruk
Copyright Year	2009
Abstract	In the present study, the effects of chronic ethanol (ETOH) treatment on the glial fibrillary acidic protein (GFAP) immunoreactivity was investigated in adult rat brains. ETOH were administered as increasing concentrations of 2.4%-7.2% (v/v) gradually for 21 days. Immunocytochemistry revealed that chronic-ETOH treatment increased synthesis of GFAP. The increase in the diameter and the number of GFAP (+) cells were statistically significant compared with the control group (p <. 05). An increase of GFAP immunoreactivity was evident in various white matter and gray matter structures. We concluded that functional astrocytic cells responded to chronic ETOH exposure by increasing the synthesis of GFAP.
Starting Page	1568
Ending Page	1578
Page Count	11
File Format	PDF HTM / HTML
Alternate Webpage(s)	http://akademikpersonel.kocaeli.edu.tr/melda/sci/melda06.09.2009_11.04.47sci.pdf
PubMed reference number	19922358v1
Volume Number	119
Issue Number	9
Journal	The International journal of neuroscience
Language	English
Access Restriction	Open
Subject Keyword	Acids Brain Chronic Lymphocytic Leukemia Diameter (qualifier value) Ethanol GFAP gene Glial Fibrillary Acidic Protein Gray Matter Immunocytochemistry Neuroglia Percent Volume per Volume Volume fraction White matter
Content Type	Text
Resource Type	Article

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