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An efficient solventless synthesis of cycloalkeno-1,2,3-selenadiazoles, their antimicrobial studies, and comparison with parent semicarbazones
| Content Provider | Semantic Scholar |
|---|---|
| Author | Jadhav, Aditi A. Dhanwe, Vaishali P. Joshi, Prasad G. Khanna, Pawan K. |
| Copyright Year | 2015 |
| Abstract | A series of heterocyclic organoselenium compounds, cycloalkeno-1,2,3-selenadiazoles (cyclopenteno, cyclohexeno, cyclohepteno, and cycloocteno-1,2,3-selenadiazoles), was synthesized at room temperature in one step under solventless conditions from the corresponding semicarbazones. The synthesized 1,2,3-selenadiazoles and their parent semicarbazones were screened for their antimicrobial activity against various pathogenic bacteria using agar disc diffusion method. All compounds were found active against E. coli, S. aureus, S. typhi, and P. aeruginosa. Among all the tested selenadiazoles, cyclopenteno-1,2,3-selenadiazole showed excellent inhibition against highly resistant P. aeruginosa. It is observed that selenadiazoles showed higher activity compared with the respective semicarbazones. |
| Starting Page | 102 |
| Ending Page | 106 |
| Page Count | 5 |
| File Format | PDF HTM / HTML |
| DOI | 10.1007/s10593-015-1666-9 |
| Volume Number | 51 |
| Alternate Webpage(s) | http://hgs.osi.lv/index.php/hgs/article/downloadSuppFile/2054/2137 |
| Alternate Webpage(s) | https://doi.org/10.1007/s10593-015-1666-9 |
| Journal | Chemistry of Heterocyclic Compounds |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
