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Combined squamous cell carcinoma and Merkel cell carcinoma of the vulva: Role of human papillomavirus and Merkel cell polyomavirus
| Content Provider | Semantic Scholar |
|---|---|
| Author | Chen, Chien-Heng Wu, Yih-Yiing Kuo, Kuan-Ting Liau, Jau-Yu Liang, Cher-Wei |
| Copyright Year | 2015 |
| Abstract | Merkel cell carcinoma (MCC), an uncommon and highly aggressive cutaneous malignancy, usually occurs on the sun-damaged skin of the elderly and is characterized by coexpression of neuroendocrine markers and CK20, a discriminant from other types of visceral neuroendocrine neoplasias. Since the discovery of Merkel cell polyomavirus (MCV), many researchers have confirmed its presence in about 80% of cutaneous MCCs.1 Although some cutaneous MCCs were reported to be associated with squamous cell carcinomas (SCCs), such combined cases accounted for only a minor portion and the viral status appeared to be different from pure MCC.1, 2, 3, 4 Rarely, primary MCCs occur on the female vulva,5 with or without combined SCCs,6, 7 the latter is often human papillomavirus (HPV) related. |
| Starting Page | 196 |
| Ending Page | 199 |
| Page Count | 4 |
| File Format | PDF HTM / HTML |
| DOI | 10.1016/j.jdcr.2015.04.005 |
| PubMed reference number | 27051728 |
| Journal | Medline |
| Volume Number | 1 |
| Alternate Webpage(s) | https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/9d/8c/main.PMC4808721.pdf |
| Alternate Webpage(s) | http://ftp.ncbi.nlm.nih.gov/pub/pmc/9d/8c/main.PMC4808721.pdf |
| Alternate Webpage(s) | https://doi.org/10.1016/j.jdcr.2015.04.005 |
| Journal | JAAD case reports |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
