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Nonfouling Polypeptide Brushes via Surface-initiated Polymerization of N(ε) -oligo(ethylene glycol)succinate-L-lysine N-carboxyanhydride.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Wang, Jing Gibson, Matthew I. Barbey, Raphaël Xiao, Shou-Jun Klok, Harm-Anton |
| Copyright Year | 2009 |
| Abstract | This contribution describes the preparation of nonfouling polypeptide brushes via surface-initiated ring-opening polymerization of oligo(ethylene glycol) modified L-lysine N-carboxyanhydrides. Circular dichroism experiments indicated that these surface-anchored polypeptide chains assume an α-helical conformation, which does not change between pH 4 and 9. Furthermore, nonspecific adsorption of fluorescent labeled bovine serum albumin and fibrinogen on glass slides modified with these brushes was greatly reduced compared to unmodified glass substrates. |
| File Format | PDF HTM / HTML |
| DOI | 10.1002/marc.200800744 |
| PubMed reference number | 21706667 |
| Journal | Medline |
| Volume Number | 30 |
| Issue Number | 9-10 |
| Alternate Webpage(s) | http://onlinelibrary.wiley.com/store/10.1002/marc.200800744/asset/supinfo/marc_200800744_sm_suppdata.pdf?s=2b08c22b0b97dbed871e2b0377cd8d8f2fd3e7fc&v=1 |
| Alternate Webpage(s) | https://doi.org/10.1002/marc.200800744 |
| Journal | Macromolecular rapid communications |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |