NDLI: Copper-Catalyzed Asymmetric 1,2-Addition of Grignard Reagents to 3-Acyl 2H-chromenes

Content Provider	Semantic Scholar
Author	Calvo, Beatriz Castillo Minnaard, Adriaan J.
Copyright Year	2017
Abstract	Enones in which the carbon–carbon double bond is part of the pharmacologically important 2 H -chromene (2 H -1-benzopyran) nucleus undergo asymmetric copper-catalyzed 1,2-addition of Grignard reagents. High yields and enantiomeric excesses up to 84% are obtained and access to these novel enantio-enriched tertiary alcohols is provided.
Starting Page	2624
Ending Page	2628
Page Count	5
File Format	PDF HTM / HTML
DOI	10.1055/s-0036-1588532
Volume Number	28
Alternate Webpage(s)	https://www.thieme-connect.com/media/synlett/201719/supmat/sup_st-2017-b0450-l_10-1055_s-0036-1588532.pdf
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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