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Avaliação do efeito dos antimicrobianos benzilpenicilina estreptomicina e flucitosina, no crescimento “in vitro” de Leishmania braziliensis
| Content Provider | Semantic Scholar |
|---|---|
| Author | Mello, Cíntia Xavier De Madeira, Maria De Fátima Nóbrega, Armi Wanderley Da Abrantes, Shirley |
| Copyright Year | 2010 |
| Abstract | The leishmaniases are a group of diseases caused by protozoa of the genus Leishmania. In the laboratory diagnosis of leishmaniasisisolation in culture is considered the gold standard, but has the drawback the possibility of secondary contamination by bacteria and fungi that prevent the examination. To minimize contamination are used as antibiotics benzylpenicillin and streptomycin and flucytosine as antifungal agents, however it is necessary to seek optimal concentrations for the isolation of the parasite is not jeopardized. We studied the effect of different concentrations of antibiotics (Penicillin and streptomycin) and antifungal (flucitosine) on the growth of Leishmania braziliensisin vitro. The results showed that concentrations of 1000 and 500 µg/mL flucitosine and streptomycin and 1000 and 500 U/mL penicillin showed significant inhibition of parasite growth, indicating that these substances should be used with some caution in the routine diagnosis of leishmaniasis. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | https://www.arca.fiocruz.br/bitstream/icict/12290/2/analytica_49_72-78.pdf |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
