NDLI: Valutazione della prevalenza dell'epatite B in 221 pazienti affetti da Psoriasi: correlazione con la gravità della malattia e confronto con la popolazione generale

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Valutazione della prevalenza dell'epatite B in 221 pazienti affetti da Psoriasi: correlazione con la gravità della malattia e confronto con la popolazione generale

Content Provider	Semantic Scholar
Author	Iacomucci, Marco Manna, Giambattista Moggio, Erica Grasso, Vincenzo Fornara, Luisa Cananzi, Raffaello Silvestri, Annalisa De Sangiovanni, Laura Barbarini, Giorgio Brazzelli, Valeria
Copyright Year	2009
Abstract	The purpose of this clinical retrospective study is the evaluation of HBV infection prevalence among a population of patients affected by psoriasis, in order to compare this prevalence with the general population; in this study the HBV infection positivity was related to PASI value of psoriasis in order to evaluate a possible pathogenic association between HBV infection and psoriasis. The study is composed by 221 patients affected by psoriasis. The psoriatic patients positive for HBV infection are 35, whereas the psoriatic patients negative for HBV infection are 186 (HBV infection prevalence: 15.8%); the control group of blood donors shows a HBV infection prevalence of 13.3% (506/3791 HBV infection positive patients), which is not statistically different to the percentage of psoriatic group. On the contrary the HBsAg prevalence was higher in psoriatic patients (3.2%) than in blood donor control group (0%). In HBV infected patients group the prevalence of severe psoriasis (evaluated with PASI score) is higher than the one of moderate psoriasis. Finally this study underlines the possible HBV infection role in triggering, manteining or esacerbating Psoriasis and also the importance of evaluating the serological HBV infection markers profile in psoriasis patients.
Starting Page	385
Ending Page	395
Page Count	11
File Format	PDF HTM / HTML
DOI	10.6092/2039-1404.122.419
Volume Number	122
Alternate Webpage(s)	http://riviste.paviauniversitypress.it/index.php/bsmc/article/download/419/407
Alternate Webpage(s)	https://doi.org/10.6092/2039-1404.122.419
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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