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Anxiolytic activity of Moralbosteroid, a steroidal glycoside isolated from Morus alba
| Content Provider | Semantic Scholar |
|---|---|
| Author | Gupta, Gaurav Kazmi, Imran Anwar, Firoz |
| Copyright Year | 2013 |
| Abstract | Mulberry, Morus alba L., as a non-toxic natural therapeutic agent, belongs with the family of Moraceae and has been cultivated in many Asian countries such as China, India, Korea, Japan and Thailand where the leaves were used as food for silkworms, is a natural food additive having vitamins, carbohydrates, mineral, lipids, sugars, proteins, fibers, etc. in appropriate proportion. The study aimed to evaluate the anxiolytic activity of Moralbosteroid isolated from Morus alba. The anxiolytic study was carried out on elevated plus-maze, light and dark model and open field test. It significantly increased the percentage of time spent (control = 33.27±0.59 sec) and number of entries in open arm (control = 6.39±0.72) in elevated plus-maze apparatus. In light and dark model, moralbosteroid produced significant increase in time spent (control = 54.82 ± 1.04 sec), number of crossing (control = 21.53 ± 0.85) and decrease in the duration of immobility (control = 37.22 ± 1.37 sec) in light box. In open field test, moralbosteroid show significant increase in number of rearing (control = 10.42 ± 0.13), assisted rearing (control = 6.28 ± 0.18) and number of square crossed (control = 57.51 ± 2.19). It is concluded that Moralbosteroid have therapeutic potential for managing anxiety. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://inforesights.com/phytopharmacology/files/pp4v2i9.pdf |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
