NDLI: Premature ovarian insufficiency – aetiopathology, epidemiology, and diagnostic evaluation

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Premature ovarian insufficiency – aetiopathology, epidemiology, and diagnostic evaluation

Content Provider	Semantic Scholar
Author	Rudnicka, Ewa Katarzyna Kruszewska, Jagoda Klicka, Klaudia Kowalczyk, Joanna Grymowicz, Monika Skórska, Jolanta Pięta, Wojciech Smolarczyk, Roman
Copyright Year	2018
Abstract	Premature ovarian insufficiency (POI) is defined as a cessation of ovarian function before the age of 40 years. It is associated with hypoestrogenism and loss of residual follicles, both of which lead to menstrual abnormalities, pregnancy failures, and decreased health-related quality of life. The prevalence of POI is estimated at 1% in the general population. Current European Society of Human Reproduction and Embryology (ESHRE) diagnostic criteria include: amenorrhoea or oligomenorrhoea for at least four months and increased follicle-stimulating hormone (FSH) levels > 25 IU/l measured twice (with a four-week interval). The aetiopathogenesis of the disease in most cases remains unexplained. Nevertheless, in some patients with POI, genetic abnormalities, metabolic disorders, autoimmunity, iatrogenic procedures, infections, or environmental factors have been established as underlying causes of the syndrome.
Starting Page	105
Ending Page	108
Page Count	4
File Format	PDF HTM / HTML
PubMed reference number	30357004v1
Alternate Webpage(s)	https://doi.org/10.5114/pm.2018.78550
DOI	10.5114/pm.2018.78550
Journal	Przeglad menopauzalny = Menopause review
Volume Number	17
Language	English
Access Restriction	Open
Subject Keyword	Amenorrhea Anaplastic thyroid carcinoma Autoimmune Diseases Congenital Abnormality Embryology Exclusion Follicle Stimulating Hormone Gonadorelin Hereditary Diseases Hyperprolactinemia Idiopathic Pulmonary Fibrosis Infection Menstruation Metabolic Diseases Mutation Oligomenorrhea Ovarian Failure, Premature Ovarian Follicle Patients Premature Menopause Premature ventricular contractions Stimulation (motivation) Thyroid Diseases Tooth Abnormalities diagnostic criteria
Content Type	Text
Resource Type	Article

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