To scavenge or not to scavenge: that is the question.

Content Provider	Semantic Scholar
Author	Nowak, E. Brzuszkiewicz, Anna Dauter, Miroslawa Dauter, Zbigniew Rosenbaum, Gerd
Copyright Year	2009
Abstract	Analysis of a series of diffraction data sets measured from four native as well as four nicotinic acid-soaked crystals of trypsin at 100 K shows a high variability in radiation-sensitivity among individual crystals for both nicotinic acid-soaked and native crystals. The level of radiation-sensitivity and the extent of its variability is statistically indistinguishable between the two conditions. This suggests that this potential scavenger does not have any statistically significant effect on the amount of radiation damage incurred in the crystals on X-ray irradiation. This is in contrast to previous results [Kauffmann et al. (2006), Structure, 14, 1099-1105] where only one crystal specimen was used for each condition (native and nicotinic acid-soaked).
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File Format	PDF HTM / HTML
Alternate Webpage(s)	https://mcl1.ncifcrf.gov/dauter_pubs/273.pdf
Alternate Webpage(s)	http://mcl1.ncifcrf.gov/dauter_pubs/273.pdf
Alternate Webpage(s)	http://www-conf.slac.stanford.edu/xrayradiation2010/Documents/abstracts.pdf
PubMed reference number	19690379v1
Alternate Webpage(s)	https://doi.org/10.1107/S0907444909026821
DOI	10.1107/s0907444909026821
Journal	Acta crystallographica. Section D, Biological crystallography
Volume Number	65
Part	9
Language	English
Access Restriction	Open
Subject Keyword	CDISC SEND Biospecimens Terminology Diagnostic radiologic examination Lethrinidae Niacin Radiation Damage
Content Type	Text
Resource Type	Article