NDLI: Sestrins at the crossroad between stress and aging

Content Provider	Semantic Scholar
Author	Bodmer, Rolf Bier, Ethan Karin, Michael
Copyright Year	2010
Abstract	Sestrins are a family of stress-inducible proteins that can function as antioxidants and as inhibitors of target of rapamycin complex 1. In this research perspective, we discuss the possible roles of Sestrins in diverse stress-induced patho-physiological contexts that can result in premature aging and age-related diseases. We suggest that Sestrins provide critical feedback regulation that adjust metabolic and stress responses to different environmental cues and evolutionary constraints.
Starting Page	369
Ending Page	374
Page Count	6
File Format	PDF HTM / HTML
DOI	10.18632/aging.100157
PubMed reference number	20606249
Journal	Medline
Volume Number	2
Alternate Webpage(s)	https://s3-us-west-1.amazonaws.com/paperchase-aging/pdf/MHfqf88cyj7KL5CZB.pdf
Alternate Webpage(s)	https://doi.org/10.18632/aging.100157
Journal	Aging
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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