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Estado nutricional del zinc y actividad de la enzima superóxido dismutasa en pacientes con enfermedad renal crónica en hemodiálisis
| Content Provider | Semantic Scholar |
|---|---|
| Author | Magalhães, R. C. Noleto Araújo, Camila Guedes Borges De Lima, Vanessa Batista De Sousa Neto, José Machado Moita Nogueira, Nadir Do Nascimento Marreiro, Dilina Do Nascimento |
| Copyright Year | 2011 |
| Abstract | Introduction: Chronic kidney disease promotes changes in the zinc nutritional status and in the antioxidant defense system. This study assessed the relationship between the parameters of the zinc nutritional status and the activity of superoxide dismutase in patients with chronic renal failure who are receiving hemodialysis. Methods: 134 individuals, aged between 18 and 85 years, were divided into two groups: case group (hemodialyzed patients, n = 63) and control group (n = 71). Zinc concentrations in plasma and erythrocytes were determined using the flame atomic absorption spectrophotometry technique. The activity of superoxide dismutase enzyme was determined according to Ransod kit. Results: The mean values of plasma zinc were 62.02 ± 13.59 μg/dL and 65.58 ± 8.88 μg/dL, and for erythrocytary zinc the values were 54.52 ± 22.82 μgZn/gHb and 48.01 ± 15.08 μgZn/gHb for the chronic renal patients and the control group, respectively. The activity of superoxide dismutase was significantly lower in patients when compared with the control group (p < 0.05). Conclusion: The activity of superoxide dismutase in patients with chronic renal failure undergoing hemodialysis, which is influenced by zinc concentracions, was significantly lower. There was an inadequate response of this enzyme to oxidative stress in patients undergoing hemodialysis. |
| Starting Page | 1456 |
| Ending Page | 1461 |
| Page Count | 6 |
| File Format | PDF HTM / HTML |
| DOI | 10.3305/nh.2011.26.6.5400 |
| Volume Number | 26 |
| Alternate Webpage(s) | http://scielo.isciii.es/pdf/nh/v26n6/37_original_24.pdf |
| Alternate Webpage(s) | http://www.redalyc.org/pdf/3092/Resumenes/Abstract_309226774037_2.pdf |
| Alternate Webpage(s) | http://www.redalyc.org/pdf/3092/309226774037.pdf |
| Alternate Webpage(s) | https://doi.org/10.3305/nh.2011.26.6.5400 |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
