Desenvolvimento de um protótipo de neuroestimulador para dor crônica

Content Provider	Semantic Scholar
Author	Santos, Pedro Matias Gomes, Luis
Copyright Year	2015
Abstract	This paper presents the development of a Spinal Cord Stimulator (SCS) prototype targeted to the treatment of chronic pain. A SCS system is usually comprised of a telemetric transmitter and a implantable stimulation circuit, also referred as implantable pulse generator (IPG). The transmitter acts as an external programmer, sending stimulation parameters such as signal amplitude, frequency, pulse-width and type of waveform to a modulator circuit. The stimulation circuit then applies pulses according to the specified parameters directly into the epidural space of the spinal cord with the help of electrode leads surgically implanted in the mentioned region. We first present a theoretical background on the subject of spinal cord stimulation. Then we present the methods behind our architecture and hardware selection, with a detailed view on each section. Experimental procedures done in our laboratory are also presented as well as our methods of analysis. Finally we analyze the accuracy of our prototype in comparison to commercially available SCS systems and discuss about future hardware and system architecture changes. Key-words: chronic pain. spinal cord stimulation.amplitude.frequency.pulse-width Lista de ilustracoes Figura 1 – Diagrama do Gerador de Pulsos Implantavel . . . . . . . . . . . . . . . 28 Figura 2 – Composicao interna do Controlador Externo . . . . . . . . . . . . . . . 33 Figura 3 – Fluxograma de Funcionamento do Controlador Externo . . . . . . . . . 33 Figura 4 – Diagrama de Funcionamento do Circuito Estimulador . . . . . . . . . . 36 Figura 5 – Diagrama de Fluxo do Codigo do Controlador . . . . . . . . . . . . . . 37 Figura 6 – Esquematico do CI XTR110, com os pinos indicados. . . . . . . . . . . 38 Figura 7 – Diagrama de funcionamento da logica de ativacao das Chaves . . . . . 40 Figura 8 – PCB Inferior do Controlador Externo . . . . . . . . . . . . . . . . . . . 42 Figura 9 – PCB Superior do Controlador Externo . . . . . . . . . . . . . . . . . . 42 Figura 10 – Vista Frontal do Controlador Externo . . . . . . . . . . . . . . . . . . 43 Figura 11 – Tela Inicial do Programador . . . . . . . . . . . . . . . . . . . . . . . . 43 Figura 12 – Tela de Configuracao de Parâmetros do Programador . . . . . . . . . . 44 Figura 13 – comportamento da corrente de saida do XTR110 com varias cargas . . 46 Figura 14 – Media e Barra de confianca com 99% de confianca . . . . . . . . . . . . 47 Figura 15 – Regrecao Linear e media dos valores medidos(*) . . . . . . . . . . . . . 48 Figura 16 – Estimulacao bifasica . . . . . . . . . . . . . . . . . . . . . . . . . . . . 49
File Format	PDF HTM / HTML
Alternate Webpage(s)	http://bdm.unb.br/bitstream/10483/11533/1/2015_PedroMatiasdosSantos_LuisGustavoBonifacioGomes.pdf
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article