B-thalassemia intermedia in Babylon Thalassemic centre Babil , Iraq .

Content Provider	Semantic Scholar
Author	Al-Marzoki, Jasim M.
Copyright Year	2017
Abstract	Thalassemia intermedia is a term used to define a group of patients with β thalassemia in whom the clinical severity of the disease is somewhere between the mild symptoms of the β thalassemia trait and the severe manifestations of β thalassemia major. This study was done to determine the demographic; clinical, laboratory data and management of patients with thalassemia intermedia. A retrospective study done in Babylon center for thalassemia in Babylon Maternity and Children Hospital. Seventy patients diagnosed as thalassemia intermedia were enrolled in our study, with patients age (1-18)years during a period from (July 2014-June 2016). Data were collected including : history, clinical manifestation , physical examination and management. There was no significant relation between the current age ,age at diagnosis, and duration of the disease in relation to gender, p values were (0.155,0.216,0.555) respectively. Height and weight percentile median 10 and IQR (10-25),median 10 and IQR 5-25 respectively. The mean and SD. for age at first blood transfusion were 8.1±2.6 years respectively. Serum ferritin was independent predictor of blood transfusion. Many patients with thalassemia intermedia need no blood transfusion while some patients need frequent blood transfusion. longer duration of disease, advanced current age, and higher serum ferritin level all were associated significantly with more need for blood transfusion.
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Alternate Webpage(s)	https://www.rjpbcs.com/pdf/2017_8(4)/%5B74%5D.pdf
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article