Diabetes mellitus is associated with subnormal serum levels of free testosterone in men.

Content Provider	Semantic Scholar
Author	Rhoden, Ernani Luís Ribeiro, Eduardo P. Teloken, Cláudio Souto, Carlos Ary Vargas
Copyright Year	2005
Abstract	OBJECTIVE To evaluate the relationship between diabetes mellitus (DM) and serum levels of free (FT) and total (TT) testosterone. PATIENTS AND METHODS A cross-sectional study was carried out including 746 men, of whom 116 (15.6%) were diabetics. Both groups, diabetic and nondiabetic, were paired according to age. Body mass index (BMI) and waist-to-hip ratio (WHR) were calculated, and a stratification analysis correlating DM and elevated BMI (>25 kg/m(2)) and WHR (>1) with the presence of subnormal FT and TT levels was performed. RESULTS FT and TT serum levels were subnormal in 46% and 34% of diabetics, respectively, and in 24% and 23% of nondiabetics. Subnormal FT levels were strongly correlated with DM (odds ratio (OR) 2.7; 95% confidence interval (CI) 1.8-4.1) but not with elevated BMI (OR 1.4; 95% CI 1.0-2.0). Subnormal TT levels were more strongly associated with elevated BMI and WHR (OR 2.6; 95% CI 1.7-3.9 and 2.0; 1.4-2.9) than with DM (1.7; 1.1-2.6 and 2.0; 1.3-3.2). CONCLUSION These data strongly suggest that DM is associated with subnormal FT levels, and that TT levels are influenced more by obesity and central adiposity.
Starting Page	96
Ending Page	96
Page Count	1
File Format	PDF HTM / HTML
Alternate Webpage(s)	http://www.cenegenics.com/pdf_docs/Diabetes_Mellitus_is_Associated_with_Subnormal_Serum_Levels.pdf
PubMed reference number	16153219v1
Volume Number	96
Issue Number	6
Journal	BJU international
Language	English
Access Restriction	Open
Subject Keyword	Body mass index Confidence Intervals Diabetes Mellitus Lewy Body Disease Obesity Odds Ratio Patients Stratification Testosterone Waist-Hip Ratio
Content Type	Text
Resource Type	Article