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Lewis base mediated halogenation/semipinacol rearrangement of diazo compounds: new access to α-halo-quaternary ketones.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Mao, Haibin Tang, Zhongkai Hu, Hongwen Cheng, Yixiang Zheng, Wen-Hua Zhu, Chengjian |
| Copyright Year | 2014 |
| Abstract | A novel halogenation/semipinacol rearrangement of α-diazo alcohol catalyzed by Lewis base has been developed through a carbene-free mechanism. This semipinacol transposition, initiated by an electrophilic halogenation (X = Cl(+), Br(+), and I(+)) of diazo carbon event, furnished a convenient synthetic route for the efficient synthesis of α-halo-quaternary ketones under mild conditions. |
| File Format | PDF HTM / HTML |
| DOI | 10.1039/c4cc04154b |
| Alternate Webpage(s) | http://pubs.rsc.org/en/content/getauthorversionpdf/C4CC04154B |
| Alternate Webpage(s) | http://www.rsc.org/suppdata/cc/c4/c4cc04154b/c4cc04154b1.pdf |
| PubMed reference number | 25019673 |
| Alternate Webpage(s) | https://doi.org/10.1039/c4cc04154b |
| Volume Number | 50 |
| Issue Number | 68 |
| Journal | Chemical communications |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |