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United States Patent ( 19 ) Muranishi et al . 54 POLYLACTIC ACID MICROSPHERES AND PROCESS FOR PRODUCING THE SAME 75 Inventors :
| Content Provider | Semantic Scholar |
|---|---|
| Author | Muranishi, Shozo Kansantachibana-Cho |
| Copyright Year | 2017 |
| Abstract | 56) References Cited U.S. PATENT DOCUMENTS 4, 166,800 9/1979 Fong . 424/426 Primary Examiner-Ferris H. Lander Attorney, Agent, or Firm-Jordan and Hamburg (57) ABSTRACT Polylactic acid microspheres having an average particle diameter of about 0.1 to 10 um which are produced from solution containing a physiologically active sub stance by the solvent-evaporation drying process. The microspheres are produced by emulsifying the solution in a non-solvent by the aid of ultrasonic wave. The microspheres produce a sustained release effect of the physiologically active substance. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | https://patentimages.storage.googleapis.com/21/9b/ad/3db052977c63d1/US4994281.pdf |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Patent |