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A metal-free synthesis of oxindoles by a radical addition-cyclization onto N-arylacrylamides with xanthates
| Content Provider | Semantic Scholar |
|---|---|
| Author | Wang, Shucheng Huang, Xuhu Li, Bowen Ge, Zemei Wang, Xin Li, Runtao |
| Copyright Year | 2015 |
| Abstract | A convenient, high yielding synthesis of oxindoles by metal-free di-functionalization of alkenes with xanthates has been developed. This transformation involves a radical addition/cyclization process. Various arylalkylation products including alkyl ester-, benzyl-, cyano-, ketone-, amine-, and amidesubstituted oxindoles were prepared in good to excellent yields. 2015 Elsevier Ltd. All rights reserved. Scheme 1. Alkene di-functionalization processes involving C(sp)eH/C(sp)eH coupling/cyclization/oxidative reaction. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://or.nsfc.gov.cn/bitstream/00001903-5/374872/1/1000014272235.pdf |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Alkenes Alkyl (C12-15) Benzoate Cyclization |
| Content Type | Text |
| Resource Type | Article |