NDLI: Antioxidant betalains from cactus pear (Opuntia ficus-indica) inhibit endothelial ICAM-1 expression.

Content Provider	Semantic Scholar
Author	Gentile, Carla Tesoriere, Luisa Allegra, Mario Livrea, Maria Antonia D'Alessio, Patrizia A.
Copyright Year	2004
Abstract	It has been suggested that some pigments would have antioxidant properties and that their presence in dietary constituents would contribute to reduce the risk of oxidative stress-correlated diseases. Among others, inflammatory response depends on redox status and may implicate oxidative stress. Vascular endothelial cells are a direct target of oxidative stress in inflammation. We have tested the impact of the free radical scavenger and antioxidant properties of betalains from the prickle pear in an in vitro model of endothelial cells. Here we show the capacity of betalains to protect endothelium from cytokine-induced redox state alteration, through ICAM-1 inhibition.
File Format	PDF HTM / HTML
DOI	10.1196/annals.1322.057
PubMed reference number	15650274
Journal	Medline
Volume Number	1028
Alternate Webpage(s)	https://core.ac.uk/download/pdf/53247365.pdf
Journal	Annals of the New York Academy of Sciences
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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