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Quick and reversible photocrosslinking reaction of 3-cyanovinylcarbazole nucleoside in a DNA triplex.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Fujimoto, Kenzo Yoshinaga, Hiroki Yoshio, Yasumasa Sakamoto, Takashi |
| Copyright Year | 2013 |
| Abstract | 3-Cyanovinylcarbazole nucleoside ((CNV)K), which can quickly photocrosslink to the pyrimidine base in the DNA double strand, was incorporated into a triplex forming oligonucleotide (TFO). We successfully demonstrated that (CNV)K in TFO can photocrosslink to the thymine base in Watson-Crick double-stranded DNA via anti-Hoogsteen base pairing with a few seconds of photoirradiation. |
| Starting Page | S277 |
| Ending Page | S279 |
| Page Count | 1 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://www.rsc.org/suppdata/ob/c3/c3ob40915e/c3ob40915e.pdf |
| PubMed reference number | 23764762v1 |
| Alternate Webpage(s) | https://doi.org/10.1039/c3ob40915e |
| DOI | 10.1039/c3ob40915e |
| Journal | Organic & biomolecular chemistry |
| Volume Number | 11 |
| Issue Number | 31 |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Base Pairing Base excess:SCnc:Pt:Bld:Qn:Calculated Burst-Forming Units, Erythroid DNA, Double-Stranded Nucleic Acid Strand Nucleosides Pyrimidines Thymine |
| Content Type | Text |
| Resource Type | Article |