Loading...
Please wait, while we are loading the content...
Similar Documents
Mutation rate in Duchenne muscular dystrophy.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Goswami, Hemen Chaurasia, B. D. |
| Copyright Year | 1971 |
| Abstract | The estimation of mutation rates in our own species has emerged as an integral part of human genetic research. Prerequisites for existing methods of calculating mutation rates are the total birth statistics and/or frequency of patients in the whole population. Unfortunately, no such records are being maintained adequately in India; a fact which was painfully realized by Haldane (1965). It is for this reason, that no contribution from this country has been made to the estimation of mutation rates, while data have been accumulated for various diseases in most parts of the world (see Crow, 1961; Sutton, 1965). The most common estimates have been for haemophilia and Duchenne muscular dystrophy. The last named disease was recorded during a survey during 1964 in the township of Agar. Recently (on the advice of Professor Sorsby), we tried to locate a few more cases of muscular dystrophy in the Central Province. In the present paper, family and population data are included and the mutation rate is calculated. |
| Starting Page | 4448 |
| Ending Page | 4450 |
| Page Count | 3 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://jmg.bmj.com/content/jmedgenet/8/3/310.full.pdf |
| PubMed reference number | 5097137v1 |
| Volume Number | 8 |
| Issue Number | 3 |
| Journal | Journal of medical genetics |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Agar Autosomal Dominant Emery-Dreifuss Muscular Dystrophy (disorder) Estimated Hemophilia A Hereditary Diseases Muscular Dystrophy, Duchenne Mutation Name Patients crow indian language |
| Content Type | Text |
| Resource Type | Article |
