NDLI: Premature ovarian insufficiency – hormone replacement therapy and management of long-term consequences

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Premature ovarian insufficiency – hormone replacement therapy and management of long-term consequences

Content Provider	Semantic Scholar
Author	Machura, Paulina Grymowicz, Monika Rudnicka, Ewa Katarzyna Pięta, Wojciech Calik-Ksepka, Anna Izabela Skórska, Jolanta Smolarczyk, Roman
Copyright Year	2018
Abstract	Premature ovarian insufficiency (POI) correlates with increased risk of cardiovascular diseases, osteoporosis, genitourinary syndrome, and other symptoms of prolonged oestrogen deprivation. Properly selected therapy improves the quality of women's lives and reduces the risk of mortality. There is a wide spectrum of available oestrogen and progestogen formulations restoring proper levels of serum sex steroid hormones. The treatment should be implemented at recognition of the POI and continued to at least the age of natural menopause. Transdermal oestradiol and oral or vaginal progesterone administration provide the most physiological sex steroid replacement therapy. Patients' views and individual preference according the route, dose, and regimen of hormonal treatment have to be taken into consideration in order to achieve high compliance rates. Women with POI should be managed by a multidisciplinary team, such as a gynaecologist, endocrinologist, dietitian, and psychologist.
Starting Page	135
Ending Page	138
Page Count	4
File Format	PDF HTM / HTML
Alternate Webpage(s)	https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/1d/48/MR-17-33849.PMC6196774.pdf
PubMed reference number	30357030v1
Alternate Webpage(s)	https://doi.org/10.5114/pm.2018.78559
DOI	10.5114/pm.2018.78559
Journal	Przeglad menopauzalny = Menopause review
Volume Number	17
Language	English
Access Restriction	Open
Subject Keyword	Cardiovascular Diseases Cognition Disorders Estradiol Estrogens Gonadal Steroid Hormones Gonadorelin Hormone replacement therapy Menopause Metabolic Process, Cellular Osteoporosis Ovarian Failure, Premature Patients Premature ventricular contractions Progesterone Progestins Puberty Steroid hormone Steroids Vagina estrogen deficiency
Content Type	Text
Resource Type	Article

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