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Is there a link between periampullary diverticula and biliopancreatic disease? An EUS approach to answer the question.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Bruno, Mauro Paolo Ribaldone, Davide Giuseppe Fasulo, Roberta Gaia, Silvia Marietti, Milena Risso, Alessandro Stradella, Davide Strona, Silvia Saracco, Giorgio Maria Angelis, Claudio Giovanni De |
| Copyright Year | 2018 |
| Abstract | BACKGROUND Many studies, almost all in an Endoscopic Retrograde Cholangiopancreatography (ERCP) setting, have been conducted to establish if a link exists between periampullary diverticula (PADs) and biliopancreatic diseases but the issue is still debated. AIMS The objective was to clarify the link between PADs and biliopancreatic disease, for the first time using Endoscopic Ultrasound (EUS). METHODS We retrospectively reviewed our database seeking patients scheduled for EUS with an indication that entailed the exploration of the second duodenum. For each patient with a PAD enrolled in the study, 6 controls were randomly selected. RESULTS 2475 patients met the inclusion criteria. Among them, 185 subjects with a PAD were found (prevalence 7.5%), 1110 subjects served as controls. Patients with a PAD had more frequently a history of cholangitis (8.1 vs 2.2%; OR 3.99, p < 0.001), a higher prevalence of common bile duct (CBD) dilation (44.3 vs 28.2%; OR 2, p < 0.0001) and a higher prevalence of CBD stones (34.1 vs 19.6%; OR 2.1, p < 0.0001). No differences were found about history of jaundice, acute/recurrent pancreatitis or EUS signs of chronic pancreatitis. CONCLUSION Whereas PADs were linked with history of cholangitis, CBD stones and dilation, no association was found with pancreatic diseases. |
| Starting Page | 925 |
| Ending Page | 930 |
| Page Count | 6 |
| File Format | PDF HTM / HTML |
| DOI | 10.1016/j.dld.2018.07.034 |
| PubMed reference number | 30145052 |
| Journal | Medline |
| Volume Number | 50 |
| Issue Number | 9 |
| Alternate Webpage(s) | https://iris.unito.it/retrieve/handle/2318/1676590/524107/Post%20print.pdf |
| Journal | Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
