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Antimicrobially active isoquinoline alkaloids from Litsea cubeba.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Feng, Tao Xu, Yan Cai, Xiang-Hai Du, Zhi-Zhi Luo, Xiao-Dong |
| Copyright Year | 2009 |
| Abstract | Bioassay-guided fractionation of the alkaloidal extract of the aerial part of Litsea cubeba led to the isolation of two new isoquinoline alkaloids, (+)- N-(methoxycarbonyl)-N-norboldine (1) and (+)-isoboldine beta-N-oxide (2), together with 11 known analogues (3-13). Their structures were established by extensive spectroscopic techniques and by comparing spectroscopic data with those in the literature. Compounds 1 and 4 showed antimicrobial activities. This is the first report on the presence of compounds 1, 2, 6, 8, 9, 11, and 12 in this plant and on the antimicrobial activities of 1 and 4. The bioactivities of isoquinoline alkaloids are also at least partly responsible for the pharmacological function of the folk medicinal plant Litsea cubeba. |
| Starting Page | 4828 |
| Ending Page | 4831 |
| Page Count | 4 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | https://www.thieme-connect.de/media/plantamedica/200901/supmat/856sup_10-1055_s-0028-1088344.pdf |
| PubMed reference number | 18991207v1 |
| Alternate Webpage(s) | https://doi.org/10.1055/s-0028-1088344 |
| DOI | 10.1055/s-0028-1088344 |
| Journal | Planta medica |
| Volume Number | 75 |
| Issue Number | 1 |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Ergot Alkaloids Isoquinolines Litsea cubeba fruit extract Pharmacology Plants, Medicinal Secologanin Tryptamine Alkaloids |
| Content Type | Text |
| Resource Type | Article |
