NDLI: Clinical Outcomes of Repeated Intraventricular Transplantation of Autologous Bone Marrow Mesenchymal Stem Cells in Chronic Haemorrhagic Stroke. A One-Year Follow Up

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Clinical Outcomes of Repeated Intraventricular Transplantation of Autologous Bone Marrow Mesenchymal Stem Cells in Chronic Haemorrhagic Stroke. A One-Year Follow Up

Content Provider	Semantic Scholar
Author	Fauzi, Asra Al Sumorejo, Purwati Suroto, Nur Setiawan Parenrengi, Muhammad Arifin Wahyuhadi, Joni Turchan, Agus Mahyudin, Ferdiansyah Suroto, Heri Rantam, Fedik Abdul Machfoed, Mochammad Hasan Bajamal, Abdul Hafid Lumenta, Christianto Benjamin
Copyright Year	2017
Abstract	Object Stroke, one of the most devastating diseases, is a leading cause of death and disability throughout the world and is also associated with emotional and economic problems. The main goal of this study was to investigate the clinical outcome of the intraventricular transplantation of bone marrow mesenchymal stem cells (BM-MSCs) in post-haemorrhagic stroke patients. Method This study was done consisting of eight patients with supratentorial haemorrhagic stroke, who had undergone 24 weeks of standard treatment of stroke with stable neurological deficits. All of the patients received stem cell transplantation intraventricularly using autologous BM-MSCs. Six months and Twelve months after stem cells treatment, the clinical outcomes were measured using the National Institute of Health Stroke Scale (NIHSS) and adverse effect also observed. Result The results of this study showed improvement of NIHSS score values before and after the treatment in five patients. No adverse effects or complications were detected during the 1-year observation. Conclusion Intraventricular transplantation of BM-MSCs has shown benefits in improving the functional status of post-haemorrhagic stroke patients with no adverse effect.
Starting Page	74
Ending Page	83
Page Count	10
File Format	PDF HTM / HTML
DOI	10.2174/1874205X01711010074
Alternate Webpage(s)	https://www.benthamopen.com/contents/pdf/TONEUJ/TONEUJ-11-74.pdf
PubMed reference number	29290837
Alternate Webpage(s)	https://doi.org/10.2174/1874205X01711010074
Journal	Medline
Volume Number	11
Journal	The open neurology journal
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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