Severe hyperphosphatemia after oral laxative administration in a 7-year-old patient.

Content Provider	Semantic Scholar
Author	Ödek, Çağlar Kendirli, Tanıl Yaman, Ayhan Sümer Kurt-Şükür, Eda Didem Telli, Onur Burgu, Berk Özçakar, Zeynep Birsin
Copyright Year	2016
Abstract	Sodium phosphate based laxatives are commonly used for constipation and pre-procedural bowel cleansing. Phosphate intoxication related with these preparations is well recognized. Herein, we present a case of severe hyperphosphatemia and seizure in a 7-year-old male patient after administration of an oral sodium phosphate based laxative. At the time of admission, serum phosphorus level was 25.6 mg/dl. Aggressive fluid therapy was started. Although serum phosphorus level decreased to 20.9 mg/dl eight hours after admission, hemodialysis was performed because of the preexisting renal disease and declined glomerular filtration rate. Serum phosphorus level and blood gas analysis returned to normal after hemodialysis and the patient was discharged on hospital day two. In conclusion, sodium phosphate based laxatives should be used carefully in patients with preexisting renal diseases. Intravenous hydration and correction of hypocalcemia are important components of treatment. Hemodialysis is indicated in patients with renal failure.
Starting Page	116
Ending Page	118
Page Count	3
File Format	PDF HTM / HTML
Alternate Webpage(s)	http://www.turkishjournalpediatrics.org/uploads/pdf_TJP_1568.pdf
PubMed reference number	27922249v1
Volume Number	58
Issue Number	1
Journal	The Turkish journal of pediatrics
Language	English
Access Restriction	Open
Subject Keyword	Constipation Fluid Therapy Glomerular Filtration Rate Hemodialysis Hyperphosphatemia (disorder) Hypocalcemia Kidney Diseases Laxatives Patients Phosphorus Renal Insufficiency Seizures mg/dl sodium phosphate
Content Type	Text
Resource Type	Article