NDLI: Comparison of monoclonal and polyclonal enzyme immunoassays for carcinoembryonic antigen.

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Comparison of monoclonal and polyclonal enzyme immunoassays for carcinoembryonic antigen.

Content Provider	Semantic Scholar
Author	Fleuren, Harry L. J. Oers, R. H. Van
Copyright Year	1986
Abstract	A new commercially available CEA immunoassay, using monoclonal antibody, was evaluated for the purpose of routine clinical use. The between-day coefficient of variation was 5.2% at the 6.6 micrograms/l level and 4.1% at the 14.2 micrograms/l level. The results of analysis of sera from 260 patients were compared with the data from an established method with polyclonal antiserum. A good correlation between the two methods was found. When the patients were classified according to groups with known types of carcinomas no systematic differences between the monoclonal and polyclonal modes of assay were apparent. Relatively large differences in serum CEA levels did occur in individual patients necessitating a transition period in changing from one method to the other.
Starting Page	E6
Ending Page	E6
Page Count	1
File Format	PDF HTM / HTML
Alternate Webpage(s)	http://edoc.hu-berlin.de/oa/degruyter/cclm.1986.24.10.741.pdf
PubMed reference number	3537198v1
Volume Number	24
Issue Number	10
Journal	Journal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie
Language	English
Access Restriction	Open
Subject Keyword	Carcinoembryonic Antigen Carcinoma Classification Coefficient Enzyme Immunoassay Immune Sera Immunoassay method Immunoenzyme Procedure Monoclonal Antibodies Patients
Content Type	Text
Resource Type	Article

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