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Highly enantioselective hydrogenation of enamides catalyzed by chiral phosphoric acids.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Li, Guilong Antilla, Jon C. |
| Copyright Year | 2009 |
| Abstract | A highly enantioselective hydrogenation of enamides catalyzed by a dual chiral-achiral acid system was developed. By employing a substoichiometric amount of a chiral phosphoric acid and acetic acid, catalyst loadings as low as 1 mol % of the chiral catalyst were sufficient to provide excellent yield and enantioselectivity of the reduction product. |
| File Format | PDF HTM / HTML |
| DOI | 10.1021/ol802860u |
| PubMed reference number | 19199770 |
| Journal | Medline |
| Volume Number | 11 |
| Issue Number | 5 |
| Alternate Webpage(s) | http://www.canli.dicp.ac.cn/Gruop%20Seminars%20Pdf/20090328tchang.pdf |
| Alternate Webpage(s) | https://doi.org/10.1021/ol802860u |
| Journal | Organic letters |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |