NDLI: Analyse de la distribution des génotypes du virus du papillome humain dans les néoplasies anogénitales et de la tête et du cou en Afrique comparativement au reste du monde

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Analyse de la distribution des génotypes du virus du papillome humain dans les néoplasies anogénitales et de la tête et du cou en Afrique comparativement au reste du monde

Content Provider	Semantic Scholar
Author	Ndiaye, Cathy
Copyright Year	2013
Abstract	Human papillomavirus (HPV) infection is the most common sexually transmitted infection worldwide. Several studies have shown its involvement in the etiology of virtually all cancers of the cervix, which is a major health problem in poor countries. HPV is also responsible for 90% of anal cancers, 40-50% of penile, vulvar and vaginal cancers, and 30% of head and neck cancers. The overall objective of this thesis is to fill the gaps in knowledge on the genotype distribution of HPV in anogenital and head and neck neoplasia, especially in sub-Saharan Africa. The specific objectives are to: 1) analyze HPV genotype distribution in cervical cancer and compare this distribution in five African countries according to HIV prevalence; 2) evaluate the presence of HPV in cancers of the head and neck in Senegal; 3) review the literature on the distribution of HPV in cancers of the head and neck in all regions of the world and perform a meta-analysis. For the first and second objectives, which were derived from a larger international project coordinated by the Catalan Institute of Oncology for the World Health Organization (WHO), a cross-sectional multicentric study was conducted to collect paraffin-embedded blocks of invasive cervical cancer and head and neck cancer diagnosed between 2001 and 2010 in Mali and Senegal. For the third objective, a comprehensive search of the literature was conducted to identify all articles published to date on head and neck cancer. A meta-
File Format	PDF HTM / HTML
Alternate Webpage(s)	https://papyrus.bib.umontreal.ca/xmlui/bitstream/handle/1866/9219/Ndiaye_Cathy_2012_these.pdf?isAllowed=y&sequence=2
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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