NDLI: Highly active antiretroviral treatment does not increase sexual risk behaviour among French HIV infected injecting drug users.

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Highly active antiretroviral treatment does not increase sexual risk behaviour among French HIV infected injecting drug users.

Content Provider	Semantic Scholar
Author	Bouhnik, - Moatti, Jean Paul Vlahov, David Gallais, Hervé Dellamonica, Pierre Obadia, Yolande
Copyright Year	2002
Abstract	STUDY OBJECTIVE This study examined the impact of highly active antiretroviral therapies (HAART) on sexual risk behaviours of HIV infected injecting drug users (IDUs) included in the French MANIF 2000 cohort study. DESIGN Longitudinal analysis including baseline and last follow up characteristics using generalised estimating equations (GEE). SETTING Hospital departments for specialist AIDS care in south eastern France and inner suburbs of Paris. PATIENTS All patients antiretrovial treatment naive, who reported being sexually active at enrollment, and who had at least one follow up visit in the cohort between October 1996 and May 1998 (n=188). MAIN RESULTS Of the 188 HIV infected IDUs who were antiretroviral treatment naive at enrollment, 34 were prescribed HAART during follow up. Proportion of patients who reported at least one episode of unprotected sexual intercourse in the previous six months only significantly decreased in the HAART treated group (from 47.1% to 23.5%, p=0.008, compared with 43.5% to 35.7% in the rest of the sample, p=0.10). GEE multivariate model confirmed that prescription of HAART was associated with reduced sexual risk. CONCLUSIONS The concern that HAART might result in clinical improvement leading to resumption of high risk activities that could inadvertently result in HIV transmission was not supported by these data. Reasons for further reductions in HIV risk with taking HAART remain to be clarified.
Starting Page	1913
Ending Page	1921
Page Count	9
File Format	PDF HTM / HTML
Alternate Webpage(s)	http://jech.bmj.com/content/jech/56/5/349.full.pdf
PubMed reference number	11964431v1
Volume Number	56
Issue Number	5
Journal	Journal of epidemiology and community health
Language	English
Access Restriction	Open
Subject Keyword	Acquired Immunodeficiency Syndrome Coitus Drug abuser Estimated Generalized abnormality of skin HIV Infections High Risk Acute Leukemia Hospital Departments Patients Physiological Sexual Disorders
Content Type	Text
Resource Type	Article

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