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Muscle atrophy, pain, and damage in bed rest reduced by resistive (vibration) exercise.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Miokovic, Tanja Armbrecht, Gabriele Gast, Ulf Rawer, Rainer Roth, Heinz Juergen Runge, Martin Felsenberg, Dieter Belavý, Daniel L. |
| Copyright Year | 2014 |
| Abstract | UNLABELLED The purpose of this study was to investigate the effectiveness of a short-duration (5-6 min, 3 d·wk) resistive exercise program with (RVE) or without (RE) whole-body vibration in reducing muscle atrophy in the lower limb during prolonged inactivity when compared with that in an inactive control group. METHODS As part of the second Berlin BedRest Study, 24 male subjects underwent 60 d of head-down tilt bed rest. Using magnetic resonance imaging, muscle volumes of the individual muscles of the lower limb were calculated before and at various intervals during and after bed rest. Pain levels and markers of muscle damage were also evaluated during and after bed rest. Adjustment of P values to guard against false positives was performed via the false discovery rate method. RESULTS On the "intent-to-treat" analysis, RE reduced atrophy of the medial and lateral gastrocnemius, soleus, vasti, tibialis posterior, flexor hallucis longus, and flexor digitorum longus (P ≤ 0.045 vs control group) and RVE reduced atrophy of the medial and lateral gastrocnemius and tibialis posterior (P ≤ 0.044). Pain intensity reports after bed rest were lower in RE at the foot (P ≤ 0.033) and whole lower limb (P = 0.01) and in RVE at the thigh (P ≤ 0.041), lower leg (P ≤ 0.01), and whole lower limb (P ≤ 0.036). Increases in sarcomere-specific creatine kinase after bed rest were less in RE (P = 0.020) and RVE (P = 0.020). No differences between RE and RVE were observed. CONCLUSIONS In conclusion, a short-duration RVE or RE can be effective in reducing the effect of prolonged bed rest on lower extremity muscle volume loss during bed rest and muscle damage and pain after bed rest. |
| File Format | PDF HTM / HTML |
| DOI | 10.1249/MSS.0000000000000279 |
| PubMed reference number | 24561811 |
| Journal | Medline |
| Volume Number | 46 |
| Issue Number | 8 |
| Alternate Webpage(s) | https://f3e7694c-a-62cb3a1a-s-sites.googlegroups.com/site/daniellbelavy/Miokovic%202014%20MSSE.pdf?attachauth=ANoY7cqxX0fH96NDosuCfMgwnmq9FJpgEgmpGXhcKf7hAfWoaDamoF2Vhmq7dCryFQmsC0va60lP0Wb7IgN-6b7y867pBcUJQHRJ6GyY8D-1hzb8KpSAhQa1osWOi_8rmsbSpykVgdahuiP9HqbUOYGE8Pg_YpaD1pI33kdS35gcDIuMbAyJ-ENTRjP5ugtcY1uVdeaaecvYNZJXt7M0hwxLs2983Wit1aOYAWjUXan3I2Cf_yrMbuI%3D&attredirects=0&d=1 |
| Alternate Webpage(s) | https://doi.org/10.1249/MSS.0000000000000279 |
| Journal | Medicine and science in sports and exercise |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
