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An X-linked tumor suppressor in T-ALL.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Ariës, Ingrid M. Gutierrez, Alejandro |
| Copyright Year | 2015 |
| Abstract | In this issue of Blood , Van der Meulen et al demonstrate that the lysine demethylase UTX (also known as KDM6A), best known as an “eraser” of methylation at histone 3 lysine 27 (H3K27), is an X-linked tumor suppressor in T-cell acute lymphoblastic leukemia (T-ALL).[1][1] This finding is |
| Starting Page | 3 |
| Ending Page | 4 |
| Page Count | 2 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://www.bloodjournal.org/content/bloodjournal/125/1/3.full.pdf?sso-checked=true |
| PubMed reference number | 25554741v1 |
| Alternate Webpage(s) | https://doi.org/10.1182/blood-2014-11-607838 |
| DOI | 10.1182/blood-2014-11-607838 |
| Journal | Blood |
| Volume Number | 125 |
| Issue Number | 1 |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Histone H3 Lysine 27 Histones KDM6A gene KDM6A wt Allele Leukemia, B-Cell Methyltransferase Neoplasms Precursor Cell Lymphoblastic Leukemia Lymphoma Precursor T-Cell Lymphoblastic Leukemia-Lymphoma Tumor Suppressor Genes X-Linked Combined Immunodeficiency Diseases lymphoblast |
| Content Type | Text |
| Resource Type | Article |
