Two-dimensional saccade-related population activity in superior colliculus in monkey.

Content Provider	Semantic Scholar
Author	Anderson, Russell W. Keller, E. L. Gandhi, Neeraj J. Das, Saumya
Copyright Year	1998
Abstract	The two-dimensional distribution of population activity in the superior colliculus (SC) during saccadic eye movements in the monkey was estimated using radial basis functions. To make these ensemble activity estimates, cells in the deeper layers of the SC were recorded over much of the rostrocaudal (caudal to 3.8 mm from the rostral tip), mediolateral extent of this structure. The dynamic movement field of each cell was determined at 2-ms intervals around the time of saccades for a wide variety of horizontal and oblique movements. Collicular neurons were divided into partially overlapping dorsal and ventral cell layers on the basis of recorded depth in SC. The pattern of presaccadic activity was used as an additional discriminant to sort the cells in the two layers into separate burst (dorsal) and buildup (ventral) cell classes. Rostrocaudal and medioventral cell location on the colliculus was estimated from the optimal target vector for a cell's visual response rather than from the optimal motor vector. The former technique was more reliable for locating some buildup neurons because it produced locations that compared better with the locations suggested by electrical stimulation. From the movement field data and from the estimates of each cell's anatomic location, a similar algorithm was used to compute the two-dimensional population activity in the two layers of the SC during horizontal and oblique saccades. A subset of the sample of neurons, located near the horizontal meridian of the SC, first was used to compute one-dimensional dynamic population activity estimates for horizontal saccades to allow partial comparison to previous studies. Statistical analyses on the one-dimensional data were limited to saccades of
Starting Page	798
Ending Page	817
Page Count	20
File Format	PDF HTM / HTML
Alternate Webpage(s)	http://wexler.free.fr/library/files/anderson%20(1998)%20two-dimensional%20saccade-related%20population%20activity%20in%20superior%20colliculus%20in%20monkey.pdf
Alternate Webpage(s)	http://www.pitt.edu/~neg8/rajimages/pdf/1998-798.pdf
PubMed reference number	9705470v1
Volume Number	80
Issue Number	2
Journal	Journal of neurophysiology
Language	English
Access Restriction	Open
Subject Keyword	Anatomic Site Buildup Caudal Class Corpora quadrigemina, superior colliculus Electric stimulation technique Estimated Eye Movements Large Meridians Monkeys Movement Saccades Subgroup algorithm anatomical layer
Content Type	Text
Resource Type	Article