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Switching the H-bonding network of a foldamer by modulating the backbone chirality and constitutional ratio of amino acids.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Ramesh, Veera V. E. Vijayadas, Kuruppanthara N. Dhokale, Snehal A. Gonnade, Rajesh G. Rajamohanan, Pattuparambil Ramanpillai Sanjayan, Gangadhar J. |
| Copyright Year | 2013 |
| Abstract | This communication describes the folding propensity of a heterofoldamer motif featuring proline (Pro) and anthranilic acid (Ant) residues in a 1:2:1 (α:β:α) constitutional ratio. Structural investigations unequivocally suggest that the hydrogen-bonding network of this foldamer motif can be switched between 9-membered and 6-membered by modulating the backbone chirality and constitutional ratio of the amino acid residues. |
| Starting Page | 1744 |
| Ending Page | 1746 |
| Page Count | 3 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://www.rsc.org/suppdata/ob/c3/c3ob41369a/c3ob41369a.pdf |
| PubMed reference number | 24057152v1 |
| Alternate Webpage(s) | https://doi.org/10.1039/c3ob41369a |
| DOI | 10.1039/c3ob41369a |
| Journal | Organic & biomolecular chemistry |
| Volume Number | 11 |
| Issue Number | 41 |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Amino Acids Proline Protein Domain Pyschological Bonding Vertebral column anthranilic acid |
| Content Type | Text |
| Resource Type | Article |