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Differential role of granule cells in the specification of synapses between climbing fibers and cerebellar Purkinje cells in the rat
| Content Provider | Semantic Scholar |
|---|---|
| Author | Delhaye-Bouchaud, Nicole Mory, Gbané Crépel, Françis |
| Copyright Year | 1978 |
| Abstract | Abstract The effect of X-irradiation of the cerebellum during postnatal development on the establishment of olivo-cerebellar connections was investigated in the rat. Treatment with 950 R during the first week led to a persistance in the adult of multiple innervation of Purkinje cells (PC) by climbing fibers (CF). On the contrary, the same dose given during the second week was uneffective to prevent the establishment of the one-to-one relationship between CF and PC. These findings suggest that the regression of the multiple innervation mainly depends on early formed granule cells. |
| Starting Page | 51 |
| Ending Page | 58 |
| Page Count | 8 |
| File Format | PDF HTM / HTML |
| DOI | 10.1016/0304-3940(78)90047-2 |
| PubMed reference number | 19605193 |
| Journal | Medline |
| Volume Number | 9 |
| Alternate Webpage(s) | https://api.elsevier.com/content/article/pii/0304394078900472 |
| Alternate Webpage(s) | https://www.sciencedirect.com/science/article/pii/0304394078900472?dgcid=api_sd_search-api-endpoint |
| Alternate Webpage(s) | https://doi.org/10.1016/0304-3940%2878%2990047-2 |
| Journal | Neuroscience Letters |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
