NDLI: Clinicopathologic study of perineural invasion in rectal cancer.

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Clinicopathologic study of perineural invasion in rectal cancer.

Content Provider	Semantic Scholar
Author	Shirouzu, Kazuo Isomoto, Hiroharu Morodomi, T. Araki, Yasumi Hoshiko, M. Akagi, Yoshito Sasatomi, Teruo Kakegawa, Teruo
Copyright Year	1992
Abstract	Perineural invasion (PNI) in rectal cancer was studied, prospectively. One-hundred patients (20%) were identified as having tumors with PNI. The incidence of PNI was significantly increased in tumors with moderate or marked venous invasion (30%, 64%), with moderate or marked lymphatic permeation (37%, 72%), with liver metastasis (50%) and with peritoneal dissemination (64%). In cases of curative surgery, the incidence of PNI was significantly increased in MAC stage C2m+g or C3 (28%, 35%). There was no significant difference in the recurrence or survival rates between the patients with PNI and without PNI in MAC stage B2m+g. However, there was a significant increase in local recurrence in the patients with both PNI and lymph node metastasis (p less than 0.05). Also, the patients with PNI in MAC stage C2m+g had a significantly lower 8-year survival rate (29.1%, p less than 0.001). Multivariate analysis using Cox regression models demonstrated that PNI was an independent prognostic factor for survival.
Starting Page	3140
Ending Page	3143
Page Count	4
File Format	PDF HTM / HTML
Alternate Webpage(s)	https://www.jstage.jst.go.jp/article/kurumemedj1954/39/1/39_1_41/_pdf/-char/en
PubMed reference number	1619888v1
Volume Number	39
Issue Number	1
Journal	The Kurume medical journal
Language	English
Access Restriction	Open
Subject Keyword	Lymphadenopathy Lymphatic Diseases Neoplasms Patients Perineural Invasion Assessment Prognostic Factors Rectal Carcinoma Rectal Dosage Form Stage I Carcinoma of Bladder TUBE,RECTAL,24FR,PLASTIC B#6510 Tarlov Cysts liver metastases lymph nodes
Content Type	Text
Resource Type	Article

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